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Atropine is an alkaloid (a family of chemicals with pharmacologic activity and a common structure) that affects the nervous system. It is found in deadly nightshade (Atropa belladonna) and other plants. Some effects of atropine include blurred vision, dilated pupils, constipation, dry mouth, and dry eyes.
Atropine is available as a prescription drug, synthesized in the laboratory. It is used to help restore or control heart function. It is used in combination with other drugs to treat other health problems including diarrhea and excessive salivation (saliva production). Atropine drops (Isopto® Atropine and others) are used to dilate pupils for eye exams.
Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.
 Avoid: Reduced drug absorption/bioavailability—Avoid these supplements when taking this medication since the supplement may decrease the absorption and/or activity of the medication in the body. | Tannin-containing herbs* such as green tea, black tea, uva ursi, black walnut, red raspberry, oak, and witch hazel |
| Depletion or interference | None known |
| Side effect reduction/prevention | None known |
| Supportive interaction | None known |
| Adverse interaction | None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Tannin-containing herbs
Tannins are a group of unrelated chemicals that give plants an astringent taste. Herbs containing high amounts of tannins, such as green tea (Camellia sinensis), black tea, uva ursi (Arctostaphylos uva-ursi), black walnut (Juglans nigra),red raspberry (Rubus idaeus),oak (Quercus spp.), and witch hazel (Hamamelis virginiana), may interfere with the absorption of atropine taken by mouth.1
1. Brinker F. Herb Contraindications and Drug Interactions. Sandy, OR: Eclectic Institute, 1997, 100.
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Learn more about the authors of Using Medicines with Vitamins and Herbs
The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires February 2010.
