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Octacosanol is a waxy substance naturally present in some plant oils and is the primary component of the sugar cane extract called policosanol.
Octacosanol is a waxy substance found in vegetable oils and sugar cane (Saccharum officinarum). Another compound, called policosanol, contains a large amount of octacosanol, along with several similar compounds.
Octacosanol has been used in connection with the following conditions (refer to the individual health concern for complete information):
| Science Ratings | Health Concerns |
|---|---|
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 Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit. | |
Because octacosanol is not an essential bodily constituent, deficiencies do not occur.
When octacosanol is taken as part of policosanol, 5–10 mg of policosanol is taken twice each day with meals. For exercise performance, 1 mg per day of octacosanol has been used.
Long-term trials in humans using amounts up to 20 mg per day have not shown any negative effects.1
At the time of writing, there were no well-known drug interactions with octacosanol.
1. Pons P, Rodriguez M, Robaina C, et al. Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolaemia and tolerability to treatment. Int J Clin Pharm Res 1994;14:27–33.
Copyright © 2007 Healthnotes, Inc. All rights reserved. www.healthnotes.com
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires September 2008.
