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ScienceHealthnotes

Tocotrienols

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Tocotrienols

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Tocotrienols are members of the vitamin E family. Like vitamin E, tocotrienols are potent antioxidants against lipid peroxidation (the damaging of fats by oxidation).1 2

Where are they found?

Tocotrienols are found primarily in the oil fraction of rice bran, palm fruit, barley, and wheat germ. Supplemental sources of tocotrienols are derived from rice bran oil and palm oil distillates. Tocotrienol supplements are available in capsules and tablets.

Tocotrienols have been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings Health Concerns
3Stars

Atherosclerosis

2Stars

High Cholesterol

1Star

Stroke

3Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Who is likely to be deficient?

As it is not an essential nutrient, no deficiency state exists.

How much is usually taken?

The typical recommendation is 140 to 360 mg per day. Most studies have used 200 mg daily.

Are there any side effects or interactions?

No significant adverse effects have been reported with tocotrienols.3

Are there any drug interactions?
Certain medicines may interact with tocotrienols. Refer to drug interactions for a list of those medicines.


1. Kamal-Eldin A, Appelqvist LA. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 1996;31:671–701 [review].

2. Kamat JP, Devasagayam TPA. Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria. Neurosci Lett 1995;195:179–82.

3. Theriault A, Chao JT, Wang Q, et al. Tocotrienol: a review of its therapeutic potential. Clin Biochem 1999;32:309–19 [review].




*The information in this newsletter is for educational use only. Do not attempt to self-diagnose or treat any condition. Please consult your healthcare practitioner if you believe you may have any of the signs or symptoms discussed above before using any of the nutrients discussed.

You should also consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.
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