Massage 1/4 to 1/2 teaspoon of cream twice daily into smooth skin areas such as wrists, inner arms or thighs, throat, abdomen or chest. Premenopausal women use 14 days prior to the first day of menstruation, discontinue and repeat. Menopausal and postmenopausal women, use for 21 days, discontinue for 7 days and repeat. These are general recommendations only and may need to be modified for individual needs. Please consult your health care profession for specific situations.