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Best MSM Powder supplies OptiMSM (methylsulfonylmethane), a naturally-occurring source of organic sulfur that is easily absorbed and used by the body. MSM occurs throughout nature as part of the global "sulfur cycle." Formed in the upper atmosphere, MSM falls to earth in rain water and is then absorbed from the soil by plant life. MSM found in foods such as fresh-picked fruits and vegetables is largely lost during food processing, storage and cooking. This makes it difficult to obtain substantial amounts of MSM from dietary sources.