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Bupleurum & Dragon Bone Combination may be used when you're under occasional stress and for occasional sleeplessness. It is traditionally used to resolve occasional frustration and nervous irritability. It may be used for nervousness due to common everyday overwork and fatigue. Bupleurum & Dragon Bone is one of the most famous and important Chinese herbal formulations. It is among the most widely-consumed formulations in Japan and throughout Asia even today.