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In 2003, the Life Extension Foundation® introduced a purified resveratrol supplement that was later documented to favorably alter some of the changes in gene expression that causes us to age. On January 25, 2009, CBS News 60 Minutes featured an in-depth report on the multiple benefits that resveratrol may confer in slowing and even reversing certain aspects of aging.
What differentiates Life Extension's resveratrol: It provides 100% standardized trans-resveratrol plus a full spectrum of natural compounds from the grape that have demonstrated remarkable biological properties. Most products currently on the market contain varying quantities of trans- and cis-resveratrol, and fail to provide enough trans-resveratrol for optimal results. In addition, Life Extension has added pterostilbene, which researchers have found works in a synergistic fashion with resveratrol to activate one's 'longevity genes'.
Research funded by Life Extension has shown that a combination of low-dose (20 milligrams) resveratrol plus grapeseed extract induced many of the favorable gene expression changes seen in calorie-restricted animals. Other studies, however, have indicated that higher doses may be needed to obtain all of resveratrol's positive benefits including:
Life Extension has meticulously evaluated published studies on resveratrol and pterostilbene to establish doses people might need to take to duplicate these remarkable laboratory findings. The results of Life Extension's analysis yield a wide range of potentially effective doses of resveratrol and pterostilbene.
Resveratrol with Pterostilbene provides 100 mg of trans-resveratrol plus 120 mg of quercetin to facilitate resveratrol absorption. The pterostilbene content of this formula (250 micrograms) is equivalent to over 10 cups of blueberries.