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Healthy Joints
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It is estimated that there are between 37 to 50 million people in this country who suffer with some degree of arthritis. The vast majority of people, of course, have osteoarthritis which is a chronic, aggressive joint disease. There are multiple factors involved in the development of osteoarthritis including obesity, heredity, prior trauma or infection, metabolic disturbances and other conditions. It is clearly an age-related disorder that is not well understood. More recent studies indicate that free radical production with oxidation may play an important role in the development of this condition.

The primary treatment of osteoarthritis up to this point has been non-steroidal anti-inflammatory drugs. Multiple studies in the medical literature indicate that these drugs can increase the risk of peptic ulceration and renal failure several hundred percent over control groups. Every year there are thousands of people that are admitted to the hospital because of the side effects of these medications. Additionally, there are studies indicating that most non-steroidal anti-inflammatory medications do not have a beneficial effect on repairing joint function and may actually cause progression of osteoarthritis.

With a basic concept that oxidation plays a significant role in the development of osteoarthritis, it would seem logical that administering anti-oxidants would have a beneficial effect. In an article published in The Annals of Internal Medicine from September 1996, it was concluded that low serum levels of vitamin D did appear to be associated with an increase risk for progression of osteoarthritis of the knee. In a study from the journal Arthritis and Rheumatism, also from 1996, it was reported that high intake of anti-oxidant micronutrients, especially vitamin C, may reduce the risk of cartilage loss and disease progression in patients with osteoarthritis. In another smaller study, it was found that treatment with vitamin E 600 mg/day had a positive analgesic effect compared to the placebo group.

Two nutrients that have garnered a lot of attention the last few years have been glucosamine sulfate and chondroitin sulfate. These nutrients have been used by physicians in Europe and Asia safely and successfully for more than twenty-five years. Glucosamine sulfate, consisting of a glucose and amine molecule, provides raw material for synthesis of proteoglycans to help maintain normal cartilage metabolism. There have been numerous studies looking at the benefits of glucosamine. Almost all of the studies have used the sulfate form as opposed to the hydrochloride form. The typical dose for glucosamine sulfate is 1500 mg daily. In one large study from Portugal involving over 1200 patients treated with glucosamine sulfate for one or two months, 95% of patients reported sufficient or good clinical response.

Chondroitin sulfate likewise plays an important structural role in cartilage metabolism. Chondroitin sulfate is felt to be chondroprotective by helping attract fluid into the proteoglycan molecule. Several control studies carried out in Italy showed chondroitin sulfate to be superior to the non-steroidal anti-inflammatory medications.

SAM (S-adenosyl methionine) is a nutrient found in the body that has been shown in multiple clinical studies to be extremely effective in osteoarthritis.

Selected Products
The following are selected products available from vitacost.com.

 

NSI ArthriPower® Multi-Vitamin

An excellent product containing the the correct amounts and forms of glucosamine and chondroitin sulfate along with SAM and multiple core nutrients is Arthripower® Multi-Vitamin from NSI.

NSI Glucosamine/Chondroitin

You body uses Glucosamine natural compound, to stimulate your cells to create one of the main building blocks of joint cartilage, proteoglycans. As you age, the amount of glucosamine created by your body decreases. The result? Your cartilage and bones begin to scrape against each other, your joints become damaged, and the lubricating synovial fluid in your joint spaces becomes thin and watery.

NSI Healthy Bones

Calcium, magnesium and other minerals are essential to maintain normal bone density and development. Calcium Malate has been proven in clinical studies to completely reduce bone loss and reduce bone fracture rates by 50%. This formula offers the most effective, superior calcium available.


Atkins Arthri-Joint
Maxilife Glucosamine & Chondroitin Sulfate Formula
FlexMax Glucosamine with MSM
SAMe Plex