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Guggul
Description: Guggul (Commiphora mukul) is an extract from the nukul Myrrh tree’s stem, and is native to India. Guggul’s properties as a supplement have often been compared to niacin and Fish Oil.
Guggul extract isolates the ketonic steroid compounds (guggulsterones) from the plant. These compounds are the reason for guggul’s lipid-lowering powers.
1 Guggul lowers LDL ("bad cholesterol") while also raising levels of HDL ("good cholesterol").2

Useful in treatment of:

High cholesterol and high triglycerides: Studies have shown that guggul can lower cholesterol by about 11% and triglycerides by 17%, as well as raise HDL (good) cholesterol levels and lower LDL (bad) cholesterol levels.3,4 It may take up to 4 weeks for maximal benefit to be seen.

Atherosclerosis: Because of its lipid lowering effects, guggul may be useful in people with coronary artery disease.

Recommended Dosage: 25 mg three times daily. Take for up to three months, then stop for two weeks before resuming.

Contraindications: Patients with liver disease or Irritable Bowel Syndrome should consult a health care professional before using guggul.

References:

1Satyavati GV. Gum guggul (Commiphora mukul)—The success of an ancient insight leading to a modern discovery. Indian J Med 1988;87:327–35.
2Nityanand S, Kapoor NK. Hypocholesterolemic effect of Commiphora mukul resin (Guggal). Indian J Exp Biol 1971;9:367–77.

3Nityanand S, et al. Clinical trials with gugulipid. A new hypolipidaemic agent. J Assoc Physicians India 37(5): 323–328, 1989.
4
Agarwal RC, et al. Clinical trial of gugulipid—a new hyperlipidemic agent of plant origin in primary hyperlipidemia. Indian J Med Res 84: 626–634, 1986.

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