Jarrow Formulas SAM-e 400

Jarrow Formulas SAM-e 400 -- 400 mg - 30 Enteric-Coated Tablets

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Jarrow Formulas SAM-e 400 -- 400 mg - 30 Enteric-Coated Tablets

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Supplement Facts
Serving Size: 1 Tablet
Servings per Container: 30
Amount Per Serving% Daily Value
S-Adenosyl Methionine
(from 800 mg of SAM-e tosylate disulfate)
400 mg*
*Daily value not established.
Other Ingredients: Cellulose, silicon dioxide, glyceryl behenate, magnesium stearate (vegetable source), enteric coating (methacrylate copolymers), titanium dioxide, magnesium silicate, triethylcitrate, riboflavin, glycerol palmitostearate, medium chain triglycerides, carboxymethyl starch sodium salt and mannitol.

Suitable for vegetarians/vegans.

Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e.

Jarrow Formulas SAM-e 400 Description

  • S-Adenosyl Methionine
  • Promotes: Joint Strength • Liver Detoxification • Mood and Brain Function
  • Highest Concentration of Active S, S Form
  • Natural - Full Potency
  • Gluten Free
  • Vegan

Jarrow FORMULAS pharmaceutical grade, stabilized SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Contains More of the Active S,S Form

Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow FORMULAS SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.

SAM-e has been clinically shown to have the following benefits:

Joint Strength 

SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.

Brain Metabolism

SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).


Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.


SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.


Take 1 tablet per day on an empty stomach, or as directed by your qualified health care consultant.
Free Of
Wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts.
These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.
Jarrow Formulas SAM-e 400 -- 30 Enteric-Coated Tablets 4.8 5 24 40
Great product Increases energy and good mood. Days feel better and happier. Other brands of Sam-e gave me some anxiety and insomnia but this one doesn't. June 20, 2013
great product I feel in a better mood when I take it. May 24, 2013
I RECOMMEND --- SAM-e Yes it is true.. this product helps life "feel" a bit less stressful. I tried it, and I must say - it works. How? Who knows - who cares.... it just works. The price: Well it is a bit costly - and I wish there were more tablets in the box - but it is worth it, I have tried St. John's Wort and I think this is much better. Try it once and you more than likely, will be a believer. SAM-e.... really helps. January 5, 2012
Best one! I've tried all of the SAMe 400 mg versions put out by other companies but never really got relief until I actually spent the extra money on Jarrow's 400 mg. It does what it says on the label. When I forget to take it, I really notice the difference. Wouldn't be without it! December 27, 2011
it really works I started taking this supplement with great skepticism. After about a month I noticed a big difference in my knee and mood. Blister pak dosing is easy to take anywhere. July 3, 2010
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Frequently Bought Together:
Jarrow Formulas SAM-e 400
Jarrow Formulas SAM-e 200

Retail price together: $79.90

Vitacost price: $47.54

You Save: 40%

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