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Doctor's Best Double-Strength SAM-e 400 -- 400 mg - 60 Enteric-Coated Table

Doctor's Best Double-Strength SAM-e 400
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    $0.81 per serving

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Doctor's Best Double-Strength SAM-e 400 -- 400 mg - 60 Enteric-Coated Table

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Doctor's Best Supplements |

Doctor's Best Double-Strength SAM-e 400 Description

  • Science-Based Nutrition™
  • Helps Enhance Mood and Neural function
  • Helps Promote Joint Comfort and Mobility
  • Helps Support Liver Health and Detoxification
  • Gluten & Soy Free
  • Vegan

SAM-e (S-Adenosyl Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving your feeling unbalanced and moody. Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood.


Supplementing with SAM-e

Soloesse® Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which  helps mediate bio-chemical activity in the human body.


SAM-e and Mood and Cognitive Function

SAM-e  helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.


SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.


SAM-e and Liver Function

SAM-e helps support healthy levels of glutathione, a critical anti-oxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidyl-choline and L-cysteine, both necessary for maintaining liver health.


**Double Strength SAM-e is sealed in blister packs for freshness and stability.


Suggested Adult Use: Take 1 tablet daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.


Store in a cool dry place.

Free Of
Gluten, soy.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts
Serving Size: 1 Tablet
Servings per Container: 60
Amount Per Serving% Daily Value
S-Adenosyl Methionine (from 800 mg of SAM-e tosylate disulfate)400 mg*
*Daily value not established.
Other Ingredients: Microcrystalline cellulose, stearic acid, calcium chloride anhydrous, magnesium silicate, magnesium stearate, magnesium hydroxide, flake shellac dewaxed, glycerol, silica, arginine base, sodium alginate, calcium oxide.

Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

The product you receive may contain additional details or differ from what is shown on this page, or the product may have additional information revealed by partially peeling back the label. We recommend you reference the complete information included with your product before consumption and do not rely solely on the details shown on this page. For more information, please see our full disclaimer.
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4 Ways That Laughter Benefits Your Health

A good belly laugh does wonders for your mood—but did you also know that it has a remarkable impact on your health? Below are four benefits of laughter that confirm that laughter trumps apples as the best way to keep the doctor away.

Two Women Enjoying the Benefits of Laughter and Each Other's Company While Looking at Pictures on Phone |

1. Busts stress

Laughter functions as a stress buster by shutting down the release of stress hormones like cortisol. It also triggers the production of feel-good neurochemicals like dopamine, which have all kinds of calming, anti-anxiety benefits.

2. Relieves pain

Laughter enhances your intake of oxygen-rich air, stimulates your heart, lungs and muscles, and increases the endorphins that are released by your brain. It can also ease pain by causing the body to produce its own natural painkillers.

3. Strengthens relationships

Laughter is central to relationships. Several studies point to shared laughter as a marker of relationship well-being. The amount of laughter a couple shares is connected to how close they feel and how supported they feel by the relationship. In other words, the more laughter a couple reports, the more favorably they rate their relationship.

4. Reduces blood pressure

one of the most dangerous side effects of stress is high blood pressure (hypertension), which is also a huge risk factor for heart disease and stroke. However, since stress and laughter can’t coexist, researchers have investigated whether laughter can bring blood pressure down. Several studies show a reduction of blood pressure after laughter, such as a 2017 study in the Journal of Dental and Medical Research, where patients exposed to “humor therapy” in the form of CDs of comic shows saw a decrease in blood pressure.

So now that you know that laughter has serious health benefits, how do you boost your chuckle quotient? Can you improve your sense of humor by working it like a muscle? As it turns out, you can. These three suggestions can make humor part of your daily repertoire of experiences.

Seek out humor

Whether its comedy videos, memes, cartoons or satire, actively seek out things that make you laugh. Cut out cartoons and put them on your fridge or hang them in your office. Make humor a priority—without getting to earnest about it. Find ways to cast a comical light on even the most serious situations.

Laugh at yourself

There’s nothing like being the butt of your own jokes to spread the levity. Being able to laugh about unfortunate events means you are able to tap into a wider perspective and get much needed distance on the problem.

Laughter loves company

One oft-cited study found that you’re 30 times more likely to laugh around other people than when you are by yourself. Invite friends over to watch stand-up comedy or simply get silly with your friends. Plenty of board games are designed to elicit humor. You can also make sure you have a good joke up you sleeve to bring a twinkle to someone else’s eye—and you may end up laughing at their enjoyment in the bargain.

Finally, I would like to conclude on a humorous note. Have you heard the one about why the buddha couldn’t vacuum under the sofa? Answer: He didn’t have any attachments. That’s the power of humor—to loosen our attachment to our plight so we can accept life’s twists with amusement.

Keep the good times rolling! Try these solutions to support a healthy mood: 

Vitacost Synergy Mood Plus† with 5-HTP & St. John's Wort  |

Nature's Plus Herbal Actives NutriZAC® Mood Food |

Country Life Omega 3 Mood™  |

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